Preprogalanin 28-67, rat

Preprogalanin 28-67, rat is a synthetic research peptide in the galanin-family neuropeptide family. Galanin is a neuropeptide whose N-terminal region is particularly important for high-affinity receptor recognition. Galanin(1-29), galanin(1-16), galanin-like peptide, and related fragments or analogs are used to study GalR1, GalR2, and GalR3 signaling and the structural requirements for receptor binding.

• galanin receptor binding assays
• GalR1/GalR2/GalR3 signaling studies
• N-terminal fragment structure-activity comparisons
• neuropeptide processing and stability studies

The exact sequence, species, residue range, terminal state, labels, stereochemistry, and post-translational modifications should be considered when comparing this reagent with the native peptide. Receptor potency and assay behavior should be validated in the intended experimental system.

1. N-terminal galanin fragments and receptor binding
2. Structural requirements for galanin receptor interaction