Physalaemin

Physalaemin is an amphibian tachykinin structurally related to Substance P. It activates tachykinin receptors and has been used historically to investigate smooth-muscle contraction, salivation and neuropeptide pharmacology.

• neuropeptide receptor pharmacology
• GPCR signaling
• neuroendocrine and smooth-muscle studies
• structure-activity research

Terminal pyroglutamate, amidation and exact residue boundaries are part of the reagent identity and should be retained when comparing tachykinin or bombesin-family activity.

1. Selected peer-reviewed publication