Peptide YY (3-36), Human

PYY(3-36) is generated from PYY by DPP-4 cleavage and preferentially activates the Y2 receptor. It is an important gut-brain satiety signal studied in appetite, energy balance and gastrointestinal physiology.

• gastrointestinal hormone research
• incretin and metabolic signaling
• gut-brain axis studies
• GPCR and endocrine pharmacology

Exact peptide boundaries and C-terminal amidation are integral to product identity. In incretin studies, distinguish intact bioactive hormones from DPP-4-cleaved metabolites and analogs.

1. Selected peer-reviewed publication