PACAP (6-38), Amide, Human/Ovine/Rat

PACAP(6-38) is a truncated PACAP analog widely used as a PAC1-receptor antagonist. Removing the N-terminal five residues sharply changes pharmacology while retaining much of the PACAP-38 backbone.

• PAC1 receptor antagonism
• PACAP signaling studies
• adenylate cyclase assays
• GPCR pharmacology

PACAP(6-38) is pharmacologically distinct from agonist PACAP-27 and PACAP-38. The amidated C terminus is part of the exact reagent.

1. Selected peer-reviewed publication