PACAP (1-38), Amide, Human/Ovine/Rat

PACAP-38 is a conserved neuropeptide of the VIP/secretin/glucagon family that activates PAC1 and VPAC receptors and stimulates adenylate cyclase. It is abundant in the central and peripheral nervous systems and participates in neuroendocrine, metabolic and stress-related signaling.

• PAC1/VPAC receptor studies
• cAMP signaling
• neuroendocrine research
• insulin secretion and stress-response studies

The C-terminal amide is part of the native active form. PACAP-38 should be distinguished from PACAP-27 and the PACAP(6-38) antagonist.

1. Selected peer-reviewed publication