Ovalbumin(250-264) DEVSGLEQLESIINFEKL

Product Name
Ovalbumin(250-264) DEVSGLEQLESIINFEKL
Product Quantity
4mg
Catalog Number
LT1959-2
Molecular Weight
1719.93
Formula
C45H74N10O13
Sequence
NH2-SGLEQLESIINFEKL-COOH
Product Description
OVA (250-264) is a class I (Kb)-restricted peptide epitope of ovalbumin (OVA), presented by the class I major histocompatibility complex (MHC) molecule, H-2Kb. It is a Self-Assembling Peptide Epitope as Novel Platform for Anticancer Vaccination.
Scientific Background

Ovalbumin(250-264) DEVSGLEQLESIINFEKL is a synthetic research peptide in the ovalbumin antigen family. The listed sequence/design is NH2-SGLEQLESIINFEKL-COOH. Ovalbumin-derived peptides, especially SIINFEKL and extended precursor fragments, are standard tools for studying MHC class I antigen processing, peptide loading, and T-cell-receptor recognition.

Research Applications
  • receptor or binding assays
  • competition experiments
  • enzymatic-processing studies
  • antibody or antigen controls
  • analytical method development
  • LC-MS/HPLC reference work
  • comparative structure-activity experiments
Experimental Notes

Because this product may be a fragment, substituted analog, stereochemical variant, or terminally modified form, its activity should not be assumed to be identical to the native parent peptide. Peptide solubility, aggregation, adsorption to surfaces, and stability can vary with sequence, concentration, pH, ionic strength, and terminal modifications, so assay-specific reconstitution and storage conditions should be validated experimentally.

Selected References
  1. Formation and kinetics of MHC class I-ovalbumin peptide complexes (PMID 10951282).
  2. Functional mapping of TCR recognition of the H-2Kb ovalbumin determinant SIINFEKL (PMID 9278320).
  • 5 Units in Stock
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