Mouse TIGIT Protein (LTP10562)

Product Name
Mouse TIGIT Protein (LTP10562)
Catalog Number
LTP10562
Quantity
100ug
Price
$406 In stock
Background
TIGIT, also called Vstm3, Vsig9, and WUCAM, is a transmembrane protein in the CD28 family of the Ig superfamily proteins.IGIT is expressed at low levels on peripheral memory and regulatory CD4 T-cells and NK cells and is up-regulated following activation of these cells.
Description
Recombinant Mouse TIGIT Protein is expressed from Expi293 with His tag at the C-terminal. It contains Gly26-Thr143.
Target
TIGIT
Species
Mouse
Gene/Protein ID
NP_001139797.1
Exact Sequence
Gly26-Thr143
Molecular Weight
The protein has a predicted MW of 14 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on the Tris-Bis PAGE result.
Activity
The affinity constant of 4.00 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Mouse TIGIT Protein (LTP10562)
  • 5 Units in Stock
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