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| Mouse LRRN1 Protein (LTP10166) |
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| LTP10166 |
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| 100ug |
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$406 In stock |
| Lrrn1 is required for the formation of MHB--loss of function leads to a loss of the morphological constriction and loss of Fgf8. Cells overexpressing Lrrn1 violate the boundary and result in a loss of cell restriction between midbrain and hindbrain compartments. Lrrn1 also regulates the glycosyltransferase Lunatic Fringe, a modulator of Notch signalling, maintaining its expression in midbrain cells which is instrumental in MHB boundary formation. |
| Recombinant Mouse LRRN1 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Ser26-Ala631. |
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| LRRN1 |
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| Mouse |
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| Q61809 |
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| Ser26-Ala631 |
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| The protein has a predicted MW of 69.28 kDa. Due to glycosylation, the protein migrates to 80-90 kDa based on the Tris-Bis PAGE result. |
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| 0 |
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| C-His |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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