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| Mouse LOX1 Protein (LTP10353) |
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| LTP10353 |
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| 100ug |
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$406 In stock |
| LOX-1 is a transmembrane glycoprotein that binds to and internalizes ox-LDL.LOX-1 gene deletion in mice and anti-LOX-1 therapy has been shown to decrease inflammation, oxidative stress and atherosclerosis. LOX-1 deletion also results in damage from ischemia, making LOX-1 a promising target of therapy for atherosclerosis and related disorders. In this article we focus on the different mechanisms for regulation, signaling and the various effects of LOX-1 in contributing to atherosclerosis. |
| Recombinant Mouse LOX1 Protein is expressed from Expi293 with His tag at the N-terminal. It contains Arg60-Ile363. |
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| LOX1 |
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| Mouse |
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| Q9EQ09 |
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| Arg60-Ile363 |
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| The protein has a predicted MW of 36.1 kDa. Due to glycosylation, the protein migrates to 55-63 kDa based on the Tris-Bis PAGE result. |
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| 0 |
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| N-His |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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