MHC II Ealpha Chain (52-68)

Eα(52-68) is a canonical MHC class II peptide often used to study peptide loading, antigen presentation, MHC trafficking and CD4 T-cell recognition. It is a useful benchmark epitope in antigen-processing experiments.

• adaptive immune and antigen-presentation research
• MHC/T-cell epitope studies
• autoimmunity or infectious-disease models
• immune assay development

Exact residue boundaries, species origin and MHC restriction are integral to experimental interpretation. Use the sequence-matched epitope required by the model system.

1. Selected peer-reviewed publication