Melittin, Honey Bee

Melittin is a 26-residue amphipathic bee-venom peptide that disrupts lipid bilayers and is widely used as a model for membrane permeabilization, lytic peptide mechanisms, immune responses and peptide-lipid biophysics.

• immunology and infectious-disease research
• T-cell or innate-immune assays
• host-pathogen interaction studies
• antimicrobial or antigen-presentation research

Exact sequence, HLA restriction, disulfide connectivity, spacer chemistry and fluorescent labeling define the reagent. Use sequence- and modification-matched controls in quantitative assays.

1. Selected peer-reviewed publication