Product Name | MAADIISTIGDLVKWIIDTVNKFKK |
Product Quantity | 4mg |
Catalog Number | 5891 |
Category | Peptide |
Sequence | GspA: MAADIISTIGDLVKWIIDTVNKFKK |
Purity | >95% |
Product Description | 
GLP-1 stimulating peptide (GspA) presents in GLP-1 positive but absents in GLP-1 neutral S. epidermidis. This novel S. epidermidis peptide modulates Glucagon-21 like peptide-1 (GLP-1) levels. GLP-1 is an incretin secreted by enteroendocrine L-cells lining the gastrointestinal epithelium. GLP-1 has important functions, including promoting insulin secretion, enhancing insulin sensitivity, and increasing beta-cell mass, while also inhibiting gastric emptying and appetite. |
Scientific Background | MAADIISTIGDLVKWIIDTVNKFKK is a 25-residue synthetic peptide with the sequence Met-Ala-Ala-Asp-Ile-Ile-Ser-Thr-Ile-Gly-Asp-Leu-Val-Lys-Trp-Ile-Ile-Asp-Thr-Val-Asn-Lys-Phe-Lys-Lys. The sequence contains 4 Lys and 0 Arg residues, contributing cationic character; has a relatively high hydrophobic-residue fraction that can influence aqueous solubility and surface adsorption. These sequence-derived properties describe the reagent chemically; no specific biological activity is assigned without product-specific experimental evidence. |
Research Applications | - LC-MS/HPLC analytical method development
- sequence-specific assay controls
|
Experimental Notes | Sequence-derived chemical properties support reagent selection and experimental planning but do not establish biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended conditions. |
