LSKL Scrambled Control Peptide, SLLK-NH2

SLLK-NH2 is a sequence-scrambled tetrapeptide control for experiments using the LSKL thrombospondin-1/TGF-beta blocking peptide. It preserves the same amino-acid composition and molecular formula as LSKL while changing residue order, making it useful for distinguishing sequence-specific effects of LSKL from nonspecific effects related to peptide composition or handling.

• scrambled-peptide negative controls
• LSKL specificity studies
• TGF-beta activation experiments
• fibrosis-model controls

SLLK should be used as a control rather than assumed to reproduce the interaction-blocking activity of LSKL. Match concentration, vehicle, incubation time, and handling conditions between test and control peptides.

1. The Activation Sequence of Thrombospondin-1 Interacts with the Latency-associated Peptide to Regulate Activation of Latent Transforming Growth Factor-beta