[Leu5]-Enkephalin

Leu-enkephalin is one of the two principal endogenous enkephalin pentapeptides. Replacement of Met5 by Leu produces a distinct opioid ligand widely used in receptor, analgesia and peptidase studies.

• neuropeptide receptor pharmacology
• GPCR and cell-signaling research
• neuroscience and behavioral studies
• peptide structure-activity analysis

Species, terminal amidation, D-amino-acid configuration, disulfide connectivity and affinity labels are part of the exact reagent identity and should be preserved when comparing published assays.

1. Selected peer-reviewed publication