Catalog Number | LT8873 |
Product Name | [Leu31, Pro34]-Neuropeptide Y, Human/Rat |
Product Quantity | 1 mg |
Sequence | YPSKPDNPGEDAPAEDMARYYSALRHYINLLTRPRY-NH2 |
Molecular Weight | 4240.8 |
Purity | ≥95% |
Scientific Background | [Leu31, Pro34]-Neuropeptide Y is a 36-residue amidated NPY analog containing Leu31 and Pro34 substitutions. These substitutions alter NPY receptor pharmacology and the analog has been widely used as a non-Y2/Y1-preferring experimental ligand in studies of neuropeptide Y receptor signaling. The full-length amidated peptide retains the characteristic pancreatic-polypeptide-fold sequence framework of the NPY family. |
Research Applications | - neuropeptide Y receptor pharmacology
- Y1-family receptor signaling studies
- NPY structure-function research
- neuroendocrine peptide assays
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Experimental Notes | Receptor selectivity is assay- and species-dependent. The analog should not be described as absolutely selective for a single NPY receptor subtype without system-specific binding or functional data. |
Selected References | - LifeTein product data sheet for [Leu31, Pro34]-Neuropeptide Y
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