Leptin (93-105), Human

NVIQISNDLENLR corresponds to residues 93-105 of human leptin. Leptin is an adipocyte-derived signaling protein whose receptor-mediated actions regulate energy-balance physiology. This short sequence-defined fragment represents a discrete region of the human leptin polypeptide and is suitable for peptide-level studies such as antibody recognition, epitope mapping, analytical method development and comparative leptin-fragment research.

• leptin peptide and epitope studies
• antibody-binding and mapping experiments
• analytical peptide standards
• leptin sequence-fragment research

This product is a short leptin fragment and should not be assumed to reproduce the receptor activation or physiological effects of intact leptin. Biological activity should be established specifically for the fragment in the experimental system being used.

1. Effects of the Obese Gene Product on Body Weight Regulation in ob/ob Mice
2. In Vivo Effects of Leptin-Related Synthetic Peptides on Body Weight and Food Intake in Female Ob/Ob Mice