IRS-1 pTyr608 Peptide

Phosphorylation of IRS-1 Tyr608 generates a docking site for SH2-domain signaling proteins including PI3K regulatory subunits. This phosphopeptide supports insulin-signaling and phosphotyrosine-binding studies.

• kinase and phosphatase assays
• SH2/phosphotyrosine interaction research
• receptor signaling studies
• phosphorylation-state controls

Phosphorylation state is part of exact product identity. Phosphopeptides and corresponding nonphosphorylated controls should be treated as separate reagents in quantitative signaling experiments.

1. Selected literature record