Human NKp46/NCR1/CD335 Protein (LTP11100)

Product Name
Human NKp46/NCR1/CD335 Protein (LTP11100)
Catalog Number
LTP11100
Quantity
100ug
Price
$473 In stock
Background
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells.
Description
Recombinant Human NKp46/NCR1/CD335 Protein is expressed from Expi293 with mFc (IgG1) tag at the C-terminal. It contains Gln22-Asn255.
Target
NKp46/NCR1/CD335
Species
Human
Gene/Protein ID
O76036-1
Exact Sequence
Gln22-Asn255
Molecular Weight
The protein has a predicted MW of 52.9 kDa. Due to glycosylation, the protein migrates to 65-75 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human NKp46, mFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Nkp46 Antibody, hFc Tag with the EC50 of 18.7ng/ml determined by ELISA. See testing image for detail.
Tag
C-mFc
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human NKp46/NCR1/CD335 Protein (LTP11100)
  • 5 Units in Stock

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