Human MICA alpha 3 Protein (LTP10021)

Product Name
Human MICA alpha 3 Protein (LTP10021)
Catalog Number
LTP10021
Quantity
100ug
Price
$563 In stock
Background
MICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig?like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin..
Description
Recombinant Human MICA alpha 3 Protein is expressed from Expi293 with mFc (IgG1) tag at the N-terminal. It contains Arg105-Ser200.
Target
MICA alpha 3
Species
Human
Gene/Protein ID
NP_001276081.1
Exact Sequence
Arg105-Ser200
Molecular Weight
The protein has a predicted MW of 36.8 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human MICA alpha 3, mFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-MICA Antibody, hFc Tag with the EC50 of 76.9ng/ml determined by ELISA. See testing image for detail.
Tag
N-mFc
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human MICA alpha 3 Protein (LTP10021)
  • 5 Units in Stock
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$563.00

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