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| Human LRRC15/LIB Protein (LTP11003) |
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| LTP11003 |
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| 100ug |
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$473 In stock |
| The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. |
| Recombinant Human LRRC15/LIB Protein is expressed from CHO with His tag and Avi tag at the C-terminal. It contains Tyr22-Gly538. |
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| LRRC15/LIB |
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| Human |
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| Q8TF66-1 |
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| Tyr22-Gly538 |
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| The protein has a predicted MW of 60.7 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Human LRRC15, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-LRRC15 Antibody, hFc Tag with the EC50 of 11.1ng/ml determined by ELISA. See testing image for detail. |
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| C-His-Avi |
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| CHO |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in 20mM Tris, 120mM NaCl (pH 7.5). Normally 8% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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