Human IL-15 Protein (LTP11017)

Product Name
Human IL-15 Protein (LTP11017)
Catalog Number
LTP11017
Quantity
100ug
Price
$383 In stock
Background
Interleukin 15 (IL-15) is a widely expressed 14 kDa cytokine that is structurally and functionally related to IL-2 and plays an important role in many immunological diseases.IL-15 is a cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA.
Description
Recombinant Human IL-15 Protein is expressed from E.coli without tag. It contains Asn49-Ser162.
Target
IL-15
Species
Human
Gene/Protein ID
P40933
Exact Sequence
Asn49-Ser162
Molecular Weight
The protein has a predicted MW of 12.8 kDa same as Tris-Bis PAGE result.
Activity
Immobilized Human IL-15 at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-15RA, His Tag with the EC50 of 12.1ng/ml determined by ELISA. The affinity constant of 0.056 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Tag
No Tag
Express System
E.coli
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by SEC-HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human IL-15 Protein (LTP11017)
  • 5 Units in Stock

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