Human FcRH5/FcRL5 Protein (LTP10003)

Product Name
Human FcRH5/FcRL5 Protein (LTP10003)
Catalog Number
LTP10003
Quantity
100ug
Price
$609 In stock
Background
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent.
Description
Recombinant Human FcRH5/FcRL5 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Gln16-Gly851.
Target
FcRH5/FcRL5
Species
Human
Gene/Protein ID
AAK93971
Exact Sequence
Gln16-Gly851
Molecular Weight
The protein has a predicted MW of 92.38 kDa. Due to glycosylation, the protein migrates to 120-140 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human FcRH5, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-FcRH5 Antibody, hFc Tag with the EC50 of 12.3ng/ml determined by ELISA. See testing image for detail.
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human FcRH5/FcRL5 Protein (LTP10003)
  • 5 Units in Stock
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