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| Human Fc gamma RIIIB/CD16b (NA1) Protein (LTP10202) |
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| LTP10202 |
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| 100ug |
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$360 In stock |
| Human Fc gamma RIIIB/CD16b Protein is a receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils. |
| Recombinant Human Fc gamma RIIIB/CD16b (NA1) Protein is expressed from Expi293 with His tag at the C-terminal. It contains Gly17-Ser200. |
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| Fc gamma RIIIB/CD16b (NA1) |
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| Human |
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| AAA35881.1 |
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| Gly17-Ser200 |
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| The protein has a predicted MW of 22 kDa. Due to glycosylation, the protein migrates to 48-55 kDa based on the Tris-Bis PAGE result. |
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| The affinity constant of 0.117 uM as determined in SPR assay (Biacore T200). See testing image for detail. |
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| C-His |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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