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| Human CADM1/IGSF4A Protein (LTP10275) |
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| LTP10275 |
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| 100ug |
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$360 In stock |
| The cell adhesion molecule 1 (CADM1) is a molecule of cell adhesion with multiple functions and has been identified as a tumor suppressor gene. CADM1 has multifunctions on the pathogenesis of malignancies, and other normal cells such as immune cells. On the contrary to these cutaneous solid tumors except for Merkel cell carcinoma, cutaneous lymphomas, such as adult-T cell leukemia/lymphoma, mycosis fungoides, and Sézary syndrome, increase their CADM1 expression for the development of tumor environment. |
| Recombinant Human CADM1/IGSF4A Protein is expressed from Expi293 with His tag at the C-terminal. It contains Gln45-His374. |
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| CADM1/IGSF4A |
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| Human |
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| Q9BY67-1 |
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| Gln45-His374 |
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| The protein has a predicted MW of 38 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Human CADM1, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CADM1 Antibody, hFc Tag with the EC50 of 8.5g/ml determined by ELISA. See testing image for detail. |
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| C-His |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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