Histone H3 (27-45)

Histone H3(27-45) spans the H3K27 regulatory site and extends through the region surrounding Lys36. This internal H3 fragment provides an unmodified reference for studies of Polycomb-linked K27 methylation and neighboring H3 tail modifications.

• histone modification studies
• chromatin reader assays
• epigenetic enzyme research
• sequence-defined controls

The exact fragment boundaries and modification state define this reagent. Biological recognition can depend strongly on peptide length and chromatin context.

1. Selected histone study