Histone H3 (21-44) K36Me1-GK(Biotin)

H3K36me1 is the monomethylated form of Lys36, a residue whose methylation states participate in transcription-associated chromatin regulation. This biotinylated H3(21-44) peptide provides a defined ligand for comparing K36 methylation-state-dependent interactions.

• H3K36 methylation studies
• histone reader binding
• demethylase assays
• streptavidin pull-downs

H3K36me1, me2 and me3 are separate biochemical marks. Preserve the exact methylation state and linker chemistry when comparing enzyme or reader specificity.

1. Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing