Histone H3 (21-44) K36Ac-GK(Biotin)

H3K36ac is an acetylated histone H3 modification associated with transcriptional regulation and an acetyl/methyl switch at Lys36. The site-specific H3(21-44) biotinylated peptide provides a defined reagent for studying proteins that discriminate acetylated versus methylated H3K36 states.

• H3K36 acetylation studies
• chromatin reader binding
• histone modification crosstalk
• epigenetic assay development

K36 acetylation and K36 methylation are not interchangeable marks. This exact free-acid GK(Biotin) reagent should be matched to otherwise identical unmodified or methylated controls.

1. Histone Methyltransferases Direct Different Degrees of Methylation to Define Distinct Chromatin Domains