Catalog Number | LT9029 |
Product Name | Histone H3 (21-44) K23Me1-GK(Biotin)-NH2 |
Product Quantity | 1 mg |
Sequence | AT-K(Me1)-AARKSAPSTGGVKKPHRYRPG-GK(Biotin)-NH2 |
Molecular Weight | 2946.6 |
Purity | ≥95% |
| Scientific Background | This histone H3 tail peptide carries monomethylation at Lys23 and a C-terminal GK(Biotin)-NH2 handle. H3K23 methylation is part of the combinatorial histone code and provides a defined neighboring mark within the H3K27/H3K36 regulatory region. |
| Research Applications | - histone methylation studies
- chromatin reader binding
- streptavidin pull-down assays
- epigenetic assay development
|
| Experimental Notes | LifeTein current listing describes this as H3(21-44) but its displayed sequence corresponds to the vendor-defined construct ending in RPG-GK(Biotin)-NH2. The exact vendor sequence and amidated terminus are retained. |
| Selected References | - Quantitative Mass Spectrometry of Histones H3.2 and H3.3 in Suz12-deficient Mouse Embryonic Stem Cells Reveals Distinct, Dynamic Post-translational Modifications at Lys-27 and Lys-36
|
