Histone H3 (1-21) K4Me1-GGK(FAM)-NH2

This fluorescent H3K4me1 peptide carries FAM on a C-terminal lysine after a GG linker. The reporter enables direct fluorescence detection of methylation-state-sensitive interactions and assay development.

• fluorescent reader binding assays
• H3K4me1 interaction studies
• fluorescence polarization development
• epigenetic screening

FAM labeling changes the charge, mass and hydrophobicity relative to unlabeled H3K4me1. Protect from light and calibrate assays using the labeled construct itself.

1. Global Mapping of H3K4me1 and H3K4me3 Reveals the Chromatin State-Based Cell Type-Specific Gene Regulation in Human Treg Cells