Grb2 SH3-Binding Peptide

This proline-rich peptide is used to investigate Grb2 SH3-domain recognition. It complements phosphotyrosine/SH2 reagents by probing the second major interaction module within the Grb2 adaptor protein.

• kinase/phosphatase assays
• SH2 and SH3 interaction studies
• receptor and immune signaling
• phosphorylation-state controls

Phosphorylation state and exact motif boundaries are part of product identity. Use matched phosphorylated and nonphosphorylated sequences where quantitative comparison is required.

1. Selected literature record