gp100 (25-33), Human

This sequence-defined gp100/PMEL fragment is a melanoma-associated antigen peptide used in experimental tumor-immunology systems. It supports comparative studies of gp100-directed T-cell recognition and peptide-specific immune responses.

• Tumor-antigen and melanoma immunology research
• T-cell stimulation and recognition assays
• Epitope comparison and peptide-loading studies
• Analytical peptide controls

MHC restriction and biological response must be established in the intended experimental system. Species, haplotype and assay context can materially affect peptide presentation and T-cell recognition.

1. gp100/pmel17 as a tumor-rejection antigen
2. Melanoma-specific T-cell expansion and tumor recognition