Catalog Number | LT8890 |
Product Name | FITC-LC-Antennapedia Peptide |
Product Quantity | 1 mg |
Sequence | FITC-LC-RQIKIWFQNRRMKWKK-NH2 |
Molecular Weight | 2748.4 |
Formula | C131H189N37O25S2 |
Purity | ≥95% |
Scientific Background | FITC-LC-RQIKIWFQNRRMKWKK-NH2 is an FITC-labeled Antennapedia/penetratin cell-penetrating peptide containing a long-chain spacer between the fluorophore and peptide. Penetratin is derived from the third helix of the Drosophila Antennapedia homeodomain and is widely used to investigate peptide internalization and membrane translocation. The FITC-LC derivative enables fluorescence-based tracking in cells and model membranes. |
Research Applications | - fluorescent penetratin uptake studies
- cellular localization
- membrane translocation research
- fluorescence microscopy
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Experimental Notes | The FITC-LC modification defines a distinct chemical reagent from FAM-labeled or unlabeled penetratin. Fluorescence and uptake behavior should be validated for this specific construct and samples protected from light. |
Selected References | - Membrane interaction and cellular internalization of penetratin peptides
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