Scientific Background | FISDYSIAMDKIHQQDFVNWLLAQK-Cys(Cy5) is a 28-residue synthetic peptide with the sequence Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Cys-Tyr-Ser. The sequence contains 1 cysteine residue, which can support thiol-selective conjugation or disulfide chemistry when the thiol is available; contains multiple acidic residues (3 Asp and 0 Glu), contributing negative charge at neutral pH; contains 5 aromatic residues (Phe/Trp/Tyr), which can contribute to hydrophobic or aromatic interactions; contains a relatively high fraction of hydrophobic residues, which can influence solubility and nonspecific adsorption. No specific receptor, enzyme, pathway, disease association, or biological activity is assigned without product-specific experimental evidence. |
Experimental Notes | Sequence-derived chemical properties are provided to support reagent selection and experimental planning. They do not establish a biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended experimental conditions. |
