Cortistatin-14, Human

Cortistatin-14 is a cyclic neuropeptide structurally related to somatostatin but expressed prominently in cortical interneurons. It modulates neuronal excitability, sleep and neuroendocrine signaling.

• neuroendocrine signaling
• GPCR and hormone-receptor pharmacology
• metabolic and feeding studies
• reproductive or gastrointestinal research

Exact species, terminal amidation, disulfide connectivity and post-translational modifications such as ghrelin acylation define the reagent and can strongly alter biological activity.

1. Selected peer-reviewed publication