Corticotropin Releasing Factor (CRF), Human/Rat

CRF is a 41-residue hypothalamic peptide that coordinates the hypothalamic-pituitary-adrenal stress axis by stimulating ACTH release through CRF receptors. It is also studied in autonomic, gastrointestinal, immune and behavioral stress responses.

• hypothalamo-pituitary axis research
• GPCR and endocrine signaling
• stress, growth-hormone or reproductive studies
• melanocortin and ACTH fragment research

Exact peptide length, terminal amidation, pyroglutamate formation and affinity labeling are integral to product identity. Use sequence- and modification-matched controls for quantitative receptor or endocrine assays.

1. Selected peer-reviewed publication