Collagen Type II (259-273), Mouse

Type II collagen(259-273) contains a major arthritogenic T-cell determinant used in collagen-induced arthritis models. It supports studies of autoimmune joint inflammation, antigen recognition and tolerance.

• T-cell and antigen-presentation research
• viral or bacterial immunity
• autoimmune disease models
• vaccine and immune-monitoring assays

Exact residue boundaries, terminal modifications and MHC restriction are integral to experimental interpretation. Select the species- and model-matched epitope for quantitative immune assays.

1. Selected literature record