Cathepsin K Substrate

Abz-HPGGPQ-EDDnp is an internally quenched fluorogenic substrate for cathepsin K, a collagenolytic cysteine protease central to osteoclast-mediated bone resorption.

• protease activity assays
• viral or lysosomal protease research
• FRET-based enzyme kinetics
• inhibitor screening

Reporter/quencher chemistry and exact terminal modifications are integral to product identity. Use assay conditions appropriate for the target protease and reporter pair.

1. Selected peer-reviewed publication