C3a, Human

Human C3a is a complement-derived anaphylatoxin generated during C3 activation. It signals through C3aR and is widely studied in inflammation, leukocyte recruitment, vascular responses and innate-adaptive immune crosstalk.

• complement biology
• inflammation and innate immunity
• receptor structure-activity studies
• immune signaling research

Exact residue boundaries and terminal modifications define product identity. Complement fragments can differ substantially in receptor potency from the intact anaphylatoxin.

1. Selected peer-reviewed publication