C3a desArg, Human

C3a desArg is the carboxypeptidase-processed form of C3a lacking the C-terminal arginine. It is useful for comparing receptor activity, inflammatory signaling and metabolic effects of intact versus processed complement peptides.

• complement biology
• inflammation and innate immunity
• receptor structure-activity studies
• immune signaling research

Exact residue boundaries and terminal modifications define product identity. Complement fragments can differ substantially in receptor potency from the intact anaphylatoxin.

1. Selected peer-reviewed publication