Scientific Background | Biotin-AKEGVVAAAEKTKQGVAEAA is a 20-residue synthetic peptide with the sequence Ala-Lys-Glu-Gly-Val-Val-Ala-Ala-Ala-Glu-Lys-Thr-Lys-Gln-Gly-Val-Ala-Glu-Ala-Ala. Biotin provides an affinity handle for streptavidin-based capture or detection. The sequence is enriched in basic residues (3 Lys and 0 Arg), giving the sequence a cationic character under many aqueous conditions; contains a relatively high fraction of hydrophobic residues, which can influence solubility and nonspecific adsorption. No specific receptor, enzyme, pathway, disease association, or biological activity is assigned to this peptide without product-specific experimental evidence. |
Experimental Notes | Sequence-derived chemical properties are provided to support reagent selection and experimental planning. They do not establish a biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended experimental conditions. |