Big Gastrin-1, Human (Gastrin-34)

Big gastrin, or Gastrin-34, is a major circulating gastrin form produced from progastrin processing. It shares the receptor-active amidated C terminus with Gastrin-17 but differs in length, processing and circulating kinetics.

• bone and calcium-homeostasis research
• GPCR and gastrointestinal hormone signaling
• affinity and receptor-binding studies
• post-translational modification research

Biotin placement, gamma-carboxylation, N-terminal pyroglutamate and C-terminal amidation define the exact reagent identity. Use sequence- and modification-matched controls in quantitative studies.

1. Selected peer-reviewed publication