Beta-Amyloid (17-28)

Aβ(17-28) contains the central hydrophobic LVFFA recognition region followed by residues through Lys28. This compact fragment is useful for studying peptide self-association and the contribution of the central Aβ sequence to aggregation-related interactions.

• amyloid-beta aggregation research
• Alzheimer's disease research
• structure-function studies
• sequence-fragment controls

N-terminal truncation and fragment boundaries can substantially change solubility, metal binding and aggregation behavior. This exact sequence should therefore be treated as a distinct research reagent rather than substituted with full-length Aβ.

1. Alzheimer's beta-amyloid: insights into fibril formation and structure from Congo red binding