Catalog Number | LT8999 |
| Product Name | Beta-Amyloid (1-42), HiLyte Fluor 647-Labeled |
| Product Quantity | 0.1 mg |
| Sequence | HiLyte Fluor™ 647-DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA |
| Molecular Weight | 5499.7 |
| Purity | ≥95% |
| Scientific Background | HiLyte Fluor 647-Aβ(1-42) is a far-red fluorescent Aβ(1-42) probe suitable for low-background imaging of amyloid self-assembly, uptake and cellular interactions. Published work has used this reagent for direct observation of Aβ self-assembly in living cells. |
| Research Applications | - far-red amyloid imaging
- Aβ self-assembly studies
- cellular uptake assays
- oligomerization research
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| Experimental Notes | Labeling can influence amyloid assembly and individual fluorescent Aβ molecules should not be assumed to behave identically to unlabeled peptide. Standardize preparation and aggregation time. |
| Selected References | - How Fluorescent Tags Modify Oligomer Size Distributions of the Alzheimer Peptide
- Direct Observations of Amyloid β Self-Assembly in Live Cells
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