Beta-Amyloid (1-40), Ultra Pure, TFA

Product Name
Beta-Amyloid (1-40), Ultra Pure, TFA
Product Quantity
5mg

Product Description

Aß (1-40) together with Aß (1-42) are two major C-terminal variants of the Aß protein constituting the majority of Aßs. These undergo post-secretory aggregation and deposition in the Alzheimer's disease brain. Peptide science is expanding rapidly due to the potential applications of these biocompatible and bioactive molecules. However, their use in medicine is limited by several factors, with low solubility being a significant hurdle in early drug development. Solubility is crucial but not well understood, and no universal method exists for peptide solubilization. This review examines the challenges in dissolving peptides and the factors influencing their aggregation and evaluates various solubilization strategies. Here are some practical tips for handling difficult sequences, with a focus on challenging amyloids like amyloid beta (Aβ), insulin, and phenol-soluble modulins (PSMs). Download the reference Here.

Catalog Number
LT2459
Molecular Weight
4329.9
Formula
C194H295N53O58S1
Sequence
Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
  • 5 Units in Stock
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$1,192.32

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