Beta-Amyloid (1-40), Reverse

Reverse Aβ(1-40) contains the amino-acid composition of Aβ1-40 in reverse sequence order. It is commonly used as a sequence-order control to distinguish composition-dependent effects from native Aβ sequence-specific aggregation or biological activity.

• amyloid-beta aggregation research
• Alzheimer disease research
• sequence/control studies
• biochemical assay development

Exact fragment boundaries, sequence order and N-terminal chemistry can materially alter Aβ solubility, aggregation and recognition. Treat this construct as a distinct reagent and use matched controls.

1. Amyloid beta-protein assembly and Alzheimer disease