Beta-Amyloid (1-28)

Aβ(1-28) contains the native N terminus and central LVFFA self-recognition region while lacking the strongly hydrophobic C-terminal segment of Aβ40/42. It is a useful soluble model for sequence-specific amyloid interactions.

• amyloid-beta aggregation research
• Alzheimer disease research
• sequence/control studies
• biochemical assay development

Exact fragment boundaries, sequence order and N-terminal chemistry can materially alter Aβ solubility, aggregation and recognition. Treat this construct as a distinct reagent and use matched controls.

1. Amyloid beta-protein assembly and Alzheimer disease