Beta-Amyloid (1-16)

Aβ(1-16) contains the hydrophilic N-terminal and histidine-rich metal-binding region of amyloid-beta without the hydrophobic C-terminal aggregation domain. It is useful for metal-binding, antibody-recognition and N-terminal interaction studies.

• amyloid-beta aggregation research
• Alzheimer disease research
• sequence/control studies
• biochemical assay development

Exact fragment boundaries, sequence order and N-terminal chemistry can materially alter Aβ solubility, aggregation and recognition. Treat this construct as a distinct reagent and use matched controls.

1. Relative abundance of Alzheimer Aβ amyloid peptide variants in Alzheimer disease and normal aging