Atrial Natriuretic Peptide (ANP) (1-28), Human

Human ANP is a 28-residue cardiac hormone containing a conserved intramolecular disulfide ring. It activates guanylyl cyclase-A/NPR-A to promote natriuresis, diuresis and vasodilation and is central to cardiovascular and renal homeostasis research.

• cardiovascular and renal signaling
• natriuretic peptide receptor research
• GPCR or cyclic-GMP signaling
• vascular and smooth-muscle studies

Disulfide connectivity, amidation and exact peptide length define these vasoactive reagents. Maintain sequence- and modification-matched controls for receptor and signaling comparisons.

1. Selected peer-reviewed publication