[Asn7]-Beta-Amyloid (1-42), Tottori-Japan Mutation

The D7N Tottori mutation lies in the Aβ N-terminal region and has been associated with altered oligomer formation. The Aβ42 version provides the longer hydrophobic C-terminal context for mechanistic comparisons.

• familial Aβ mutation studies
• amyloid aggregation and oligomerization
• cerebral amyloid angiopathy research
• mutant versus wild-type comparisons

Mutation identity and Aβ length define this reagent. Compare with sequence-matched wild-type Aβ42 or the corresponding Aβ40 mutant under identical preparation conditions.

1. Selected familial amyloid mutation publication