Apelin-13

Apelin-13 is a potent endogenous peptide agonist of the apelin receptor APLNR/APJ. The N-terminal pyroglutamate form is biologically stable and is studied in cardiovascular function, fluid homeostasis, metabolism and angiogenesis.

• cardiovascular signaling
• GPCR pharmacology
• vascular and inflammatory research
• peptide structure-activity studies

Exact residue boundaries, terminal processing and pyroglutamate formation are integral to peptide identity. Compare only sequence- and modification-matched reagents in quantitative assays.

1. Selected peer-reviewed publication